Relief of Pain and Inflammation : Narcotic Analgesics
IRAPI1 “Rapifen injection” 0.544 mg/ml; 2 ml/amp
適應症：短效麻醉性止痛劑及麻醉誘導劑。
Usual dose:
Adult (≧12 yrs): IV
Surgery duration≦30 min: 8-20 mcg/kg IV, then continuous IV infusion of 0.5-1 mcg/kg/min; total dose 8-40 mcg/kg.
Surgery duration 30-60 min: 20-50 mcg/kg IV, then maintenance IV injections of 5-15 mcg/kg q5-20min; total dose up to 75 mcg/kg.
Surgery duration > 45 min: 50-75 mcg/kg IV, then continuous IV infusion of 0.5-3 mcg/kg/min.
Anesthesia: 130-245 mcg/kg induction dose followed by continuous IV infusion of 0.5-1.5 mcg/kg/min
Contraindication: Hypersensitivity to alfentanil or any component of the product, intolerance to opioid agonists.
Precaution: Not recommended in children < 12 yrs; arrhythmias, asystole, bradycardia, and hypotension.
Adverse effect:
Common: nausea, vomiting.
Serious: apnea, bradyarrhythmia, cardiac dysrhythmia, hypertension, hypotension, involuntary movement, musculoskeletal, muscle rigidity, respiratory depression, tachyarrhythmia.