Respiratory Tract Drugs: Bronchodilators
IAMIN1 “Aminophyllin injection” 25 mg/1ml; 10 ml/amp
適應症：心因性、支氣管氣喘及支氣管痙攣。
Usual dose:
Asthma and COPD: IV bolus 5 mg/kg over 20-30 min provides peak serum theophylline conc. 5-15 mg/ml; maintenance, 0.4 mg/kg/h continuous IV infusion.
Adverse effect:
Common: nausea, vomiting, headache, insomnia, tremor, restlessness, diuresis.
Serious: atrial fibrillation, bradyarrhythmia, (too quick administration), cardiac arrest, tachyarrhythmia, erythroderma, necrotizing enterocolitis in fetus or newborn, immune hypersensitivity reaction, intracranial hemorrhage, seizure.
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