Amoxicillin【B】

Anti-infective Agents : Penicillins
OAMOL1 “Amolin powder for oral suspension” 25 mg/ml; 60 ml/bot
OAMOX5 “Amoxicillin capsule” 500 mg/cap
OAMOX6 “Amoxicillin capsule” 250 mg/cap

適應症:葡萄球菌、鏈球菌、肺炎雙球菌、腦膜炎球菌,及其它具有感受性細菌引起之感染。

Usual dose:

Susceptible infections: mild-to-moderate

Adult: 500 mg q12h or 500 mg q8h.

Pediatric

(≦3 mon): 30 mg/kg/day orally divided q12h.

(> 3 mon): 25-50 mg/kg/day orally divided q8h.

Susceptible infections: severe

Adult: 875 mg q12h or 500 mg q8h; max. 1.5gm/day.

Pediatric

(≦3 mon):, 30 mg/kg/day orally divided q12h.

(> 3 mon): 25-50 mg/kg/day orally divided q8h.

Endocarditis prophylaxis:

Adult: 2 gm orally 1 h prior to procedure.

Pediatric: 50 mg/kg 1 h prior to procedure; max. 2 gm/dose.

Gonorrhea: 3 gm as a single dose.

Helicobacter pylori: 1 gm bid in combination with   clarithromycin 500 mg bid; or 1 g tid.

Dose adjustment:

Renal failure: CrCl 10-30 ml/min, usual dose q12h; CrCl < 10 ml/min, usual dose q24h.

Hemodialysis: usual dose q24h (give additional dose both during and at the end of dialysis).

Adverse effect:

Common: rash, diarrhea, nausea, vomiting.

Serious: hypersensitivity reaction.

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