Cardiovascular – Renal Drugs : Diuretics
OBURI1 “Burinex tablet” 1 mg/tab
適應症：水腫、利尿。
Usual dose:
Edema: PO/IV/IM
Adult (> 18 yrs): 0.5-2 mg PO, single dose; 0.5-1 mg IV ( over 1-2 min) or IM; can give a sec and third dose at intervals of 2-3 h to max. of 10 mg/day.
Contraindiction:
Anuria, hepatic coma, severe electrolyte depletion.
Precaution:
Alterations in glucose metabolism, blood dyscrasias; development of oliguria, elevated BUN or creatinine, hepatic disease, hyperuricemia, hypokalemia, hypomagnesemia, hypovolemia, neonates at risk for kernicterus (excessive serum bilirubin), ototoxicity.
Adverse effect:
Common: hypotension, hyperuricemia, hypokalemia, nausea, cramp, dizziness, headache.
Serious: thrombocytopenia.
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