Psychopharmacologic Drugs : Affective Disorders
OANBU1 “Anbutrine XL tablet” 150 mg/tab
OWELL5 “Wellbutrin XL tablet” 150 mg/tab
適應症:治療憂鬱症。
Usual dose:
Major depressive disorder: initial, 150 mg am for 3 days, then increase to 150 mg bid for several wks, max. 200 mg bid.
Smoking cessation, adjunct: initial 150 mg in the morning for 3 days, then increase to 150 mg bid for 7-12 wks, max. 300 mg/day; treatment should begin 1 wk before the p’ts stop smoking.
Dose adjustment:
Liver disease: < 75 mg/day.
Renal impairment: reduced frequency and/or dose.
Contraindication:
Seizure disorder, undergoing abrupt discontinuation of alcohol or sedatives, current or previous diagnosis of bulimia or anorexia nervosa.
Concomitant with other MAOIs.
Adverse effect:
Common: Insomnia, headache, dry mouth, GI disturbances, nausea, vomiting, hypersensitivity reactions, urticaria, anorexia, agitation, anxiety, tremor, dizziness, taste disorders, visual disturbances, tinnitus, hypertension, flushing, abdominal pain, constipation, rash, pruritus, sweating, fever, chest pain, asthenia.
健保使用規範:作為戒菸治療者不予給付。