Nutritional Agents : Vitamins
ICACA1 “Cacare injection” 1 mcg/ml; 1ml/amp
OMACA1 “Macalol soft capsule” 0.25 mcg/cap
OUCAS2 “U-Ca Soft Capsule” 0.5 mcg/cap
適應症：
ICACA1：處理長期腎透析病人的低血鈣情形。
OMACA1, OUCAS2：侷僂病、軟骨病、促進鈣磷吸收、維他命D缺乏症、過敏性疾患。
Usual dose:
Familial x-linked hypophosphatemic Vitamin D refractory rickets: initial, 0.015-0.02 mcg/kg qd; maintenance, 0.03-0.06 mcg/kg qd, max. 2 mcg qd.
Hypocalcemia – hypoparathyroidism, postsurgical or idiopathic: 0.5-2 mcg qd; initial, 0.25 mcg /day PO in the morning; increased at 2-4 wk intervals.
Hypocalcemia – pseudohypoparathyroidism: 0.5-2 mcg qd; initial, 0.25 mcg /day PO in morning; increased at 2-4-wk intervals.
Hypocalcemia – renal dialysis: initial, 0.25 mcg qd or qod (may require 0.5 to 1 mcg /day); increases of 0.25 mcg /day at 4-8 wk intervals.
Secondary hyperparathyroidism: initial, 0.25-0.5 mcg qd; dialysis, initial, 0.25 mcg qd or qod (may require 0.5 to 1 mcg /day); increases of 0.25 mcg /day at 4-8 wk intervals.
Precaution:
Maintain adequate hydration; protect from light.
Contraindication:
Hypercalcemia, Vitamin D toxicity.
Adverse effect:
Serious: poisoning by vitamin D, hypercalcemia syndrome.
健保使用規範：限下列病例使用：（86/1/1、91/7/1、100/1/1）
1.Vit.D依賴型佝僂症或低磷血佝僂症。(應附醫學中心之診斷証明)
2.副甲狀腺機能低下症。(應檢附病歷影本)
3.慢性腎不全引起之低血鈣症，並限腎臟功能失調 (即BUN值80 mg/dL以上或creatinine值4.0 mg/dL以上或PTH-i大於正常值三倍以上)，血中鈣濃度在10.5 mg/dL以上之病例不可使用。
4.停經後婦女患有脊椎壓迫性骨折或髖骨骨折病患。