Anti-infective Agents : Cephalosporins : First Generation Cephalosporins
OCEFA2 “Cefadroxil capsule” 500 mg/cap
適應症:革蘭氏陽性菌及陰性菌所引起之感染症。
Usual dose:
Infection of skin and/or subcutaneous tissue:
Adult: 1 gm qd or divided bid.
Pediatric: 15 mg/kg bid, max. 2 gm/day.
Pharyngitis, Tonsillitis:
Adult: 1 gm qd or divided bid for 10 days.
Pediatric: 30 mg/kg qd or divided bid for 10 days, max. 2 gm/day.
Urinary tract infectious:
Adult: complicated, 1 g bid; uncomplicated: 1-2 gm qd or divided bid.
Pediatric: 15 mg/kg bid, max. 2 gm/day.
Dose adjustment:
Renal failure: CrCl 25-50 ml/min, 500 mg q12h; CrCl 10-25 ml/min 500 mg q24h; CrCl < 10 ml/min, 500 mg q36h.
Adverse effect: rash, diarrhea, nausea, vomiting.