Anti-infective Agents : Quinolones
ICIPR1 “Ciproxin sol’n injection” 2 mg/ml; 100 ml/bot
ICIPR3 “Ciproxin sol’n injection” 2 mg/ml; 200 ml/bot
ISEFO1 “Seforce sol’n injection” 2 mg/ml; 200 ml/bot
OCIPR2 “Ciproxin FC tablet” 250 mg/tab
適應症:對ciprofloxacin有感受性之細菌所引起之呼吸道感染、中耳炎、竇炎、眼感染、腎臟及泌尿道感染(包括淋病)、腹部感染(包括腹膜炎)、皮膚及軟組織感染、骨髓炎、關節感染、菌血症。
Usual dose:
Adult: PO 500-750 mg q12h; IV 400 mg q8-12h.
UTI: PO/IV
Adult: PO 250-500 mg q12h; IV 200-400 mg q12h.
Inhalation anthrax: PO
Adult: 500 mg q12h for at least 60 days.
Pediatric:10-15 mg/kg bid for at least 60 days, max. 500 mg/dose.
Dose adjustment:
Renal failure:
IV, CrCl > 30 ml/min, give usual dose; CrCl 5-29 ml/min, 200-400 mg q18-24h.
PO: CrCl > 50 ml/min, give usual dose; CrCl 30-50 ml/min, 250-500 mg q12h; CrCl 5-29 ml/min, 250-500 mg q18h; hemodialysis/peritoneal dialysis: 250-500 mg q24h, after dialysis.
Adverse effect:
Common: rash, diarrhea, nausea, dizziness, headache, restlessness.
Serious: hypersensitivity reaction, rupture of tendon, tendonitis, peripheral neuropathy, raised intracranial pressure, seizure, drug-induced psychosis.