Anti-infective Agents : Miscellaneous antibacterials
ICOLI1 “Colimycin injection” 2000000 U/vial
適應症:限用於一般抗生素無效,且具多重抗藥性之革蘭氏陰性菌之嚴重感染。
Usual dose:
Susceptible infections: IM/IV 2.5-5 mg/kg/day in 2-4 divided doses.
Cyctic fibrosis: IV 3-8 mg/kg/day in 3 divided doses or 60-70 mg q8h, if tolerated, may increase to 80-100 mg q8h.
Adverse effect:
Dizziness, fever, headache, slurred speech, vertigo, pruritus, rash, urticaria, GI upset, paresthesia, weakness, creatinine increased, proteinuria, apnea, respiratory arrest, lung toxicity, bronchospasm, nephrotoxicity, acute respiratory failure.