Doxepin HCl【B】

Dermatological Preparations : Analgesics and Antipruritics
TICHD1“Ichderm cream” 50 mg/gm; 15 gm/tube

適應症:成人濕疹性皮膚炎(如異位性皮膚炎或單純性慢性苔癬)所致中度搔養症之短期治療。

Usual dose:

Anxiety-Depression:

Adult ( > 12 yrs): (very mild) 25-50 mg/day, (mild- moderate) 75 mg/day in single or divided doses, increase as needed; max. 300 mg/day.

Dose adjustment:

Geriatric: 25-50 mg/day.

Liver disease: begin with low initial doses.

Contraindication: glaucoma, urinary retention.

Precaution:

Concomitant use of MAOIs or use of doxepin within 14 days of MAOI discontinuation.

Adverse effect:

Common: weight gain, bloating symptom, constipation, xerostomia, dizziness, somnolence, blurred vision, urinary retention.

Serious: hypertension, hypotension, tachyarrhythmia, agranulocytosis, leukopenia, pancytopenia, purpuric disorder, thrombocytopenia, depression, worsening, suicidal thoughts, suicide.

Usual dose: applied qid, with at least 3-4 h intervals.

Adverse effect:

Agranulocytosis, depression, worsening, hypertension, hypotension, leukopenia, pancytopenia, purpuric disorder, suicidal thoughts, suicide, tachyarrhythmia, thrombocytopenic disorder.

健保使用規範:限成人使用,每次處方不超過七天。(88/6/1)

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