Efavirenz【D】

Anti-infective Agents : Antiretroviral Agents
OSTOC1 “Stocrit tablet” 600 mg/tab

適應症:用於人體免疫缺乏病毒第一型(HIV-1)感染之成人、青少年和兒童的抗病毒合併療法。

Usual dose:

HIV infection, combine with other antiretrovirals:

Adult: 600 mg qd.

Pediatric (≧3 yrs):

10-15 kg: 200 mg qd.

15-20 kg: 250 mg qd.

20-25 kg: 300 mg qd.

25-32.5 kg: 350 mg qd.

32.5-40 kg: 400 mg qd.

> 40 kg: 600 mg qd.

Contraindication: concomitant administration of astemizole, cisapride, midazolam, triazolam, ergot derivatives, or voriconazole.

Adverse effect:

Common: rash, more common in children, lipodystrophy, dizziness, insomnia, somnolence, depression, sometimes severe, dream disorder, hallucinations, unable to concentrate.

Serious: aggressive behavior, delusion of persecution, manic behavior, mental disorder, suicidal attempts.

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