Cardiovascular – Renal Drugs: Antihypertensive: Calcium-Channel Blockers
OFEDI1 “Fedil SR tablet” 5 mg/tab
OFELP1 “Felpin ER tablet”5 mg/tab
OFELO9 “Felopine ER tablet”10 mg/tab
適應症：高血壓、心絞痛。
Usual dose:
Angina pectoris:
Adult: 2.5-5 mg bid.
CHF:
Adult: initial, 5 mg qd; maintenance, 5 mg bid.
Hypertension :
Adult: initial, 5 mg qd; maintenance dose range 2.5-10 mg qd.
Pediatric: initial, 0.1 mg/kg/day in 1-2 doses; maintenance, 0.1-0.6 mg/kg/day in 1-2 doses.
Raynaud’s phenomenon:
Adult: 10-20 mg/day.
Dose adjustment:
Hepatic failure: initial, 2.5 mg qd; adjust to effect.
Geriatric: initial, 2.5 mg qd; adjust to effect.
Precaution:
Avoid taking with grapefruit juice, do not chew or crush tablets.
Adverse effect:
Common: peripheral edema, flushing, drug -induced gingival hyperplasia, dizziness, headache.
Serious: angina, hypotension, myocardial infarction, tachyarrhythmia.
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