Hormones and Agents Affecting Hormonal Mechanism: Antidiabetic Agents: Oral Hypoglycemic Agents
OJANU2 “Janumet FC tablet”
Each tablet contains sitagliptin 5 mg, metformin HCl 500 mg
適應症：適用於配合飲食和運動，以改善下列第二型糖尿病患者的血糖控制：已在接受Sitagliptin和metformin合併治療者，或僅適用Sitagliptin或metformin但控制不佳者。
Usual dose:
dosage should be individualized based on patient’s current regimen, effectiveness, and tolerability; max. sitagliptin 100 mg and metformin 2000 mg per day
Contraindication: See metformin HCl.
Adverse effect:
Common: asthenia, headache, nasopharyngitis.
Serious: Exfoliative disorder of skin of scalp, Stevens-Johnson syndrome, hypoglycemia, lactic acidosis, pancreatic cancer, pancreatitis, anaphylaxis, hypersensitivity reaction, rhabdomyolysis, abnormal renal function, acute renal failure, angioedema, pancreatic cancer.
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