Relief of Pain and Inflammation : Non-Steroidal Anti-inflammatory Agents (NSAID)
IKETO1 “Keto injection” 30 mg/ml; 1 ml/amp
ILAST1 “Laston injection” 30 mg/ml; 1 ml/amp
OKETO3 “Keto EM capsule”10 mg/cap
適應症：
IKETO1, ILAST1：短期（≦5天）使用於緩解無法口服之病人之中重度急性疼痛，通常使用於手術後。
OKETO3：疼痛之短期療法。
Usual dose:
Adult (< 65 yrs): 60 mg IM or 30mg IV for 1 dose or 30 mg IM or IV q6h, max. 120 mg/day.
Pediatric (2-16 yrs): 1 mg/kg IM for 1 dose, max. 30 mg, 0.5 mg/kg IV for 1 dose, max. 15 mg.
Dose adjustment:
Geriatric (> 65 yrs), Renal impairment: 30 mg IM for 1 dose or 15 mg IM q6h, max. 60 mg/day, 15 mg IV for 1 dose or 15 mg q6h, max. 60 mg/day.
Precaution:
IV bolus must be given > 15 sec, therapy should < 5 days, all routes combined.
Adverse effect:
Common: edema, hypertension, injection site pain, pruritus, rash, sweating symptom, abdominal pain, constipation, diarrhea, dyspepsia, flatulence, nausea, stomatitis, vomiting, anemia, purpuric disorder, dizziness, headache, somnolence.
Serious: myocardial infarction, palpitations, syncope, thrombotic tendency observations, scaling eczema, Stevens-Johnson syndrome, toxic epidermal necrolysis, gastrointestinal hemorrhage, gastrointestinal perforation, inflammatory disorder of digestive tract, melena, pancreatitis, anemia, bleeding, leukopenia, thrombocytopenic disorder, hepatitis, increased liver function test, jaundice, liver failure.
健保使用規範：注射劑限用於無法口服之病人，且為手術後中重度急性疼痛之短期治療（治療期間為≦5天），惟禁止使用於產科止痛。(97/7/1)