Leflunomide【X】

Immunologic Agents : Immunomodulators
OARAV1 “Arava tablet” 10 mg/tab
OARHE1 “Arheuma tablet” 20 mg/tab

適應症:治療成人類風濕性關節炎,並可能減緩類風濕病程對關節所造成之結構性損害(即屬於DMARD disease modifying antirheumatic drug)。治療具活動性的成人乾癬性關節炎。

Usual dose: 100 mg qd x 3 days, then 10-20 mg qd.

Precaution: not recommended in p’t with significant hepatic dysfunction or positive hepatitis B or C serologies.

Adverse effect:

Common: alopecia, rash, diarrhea.

Serious: hypertension, increased liver enzymes, Stevens-Johnson syndrome.

健保使用規範:健保藥品給付規定第八章免疫製劑。

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