Nutritional Agents : Replenishers & Regulators of Water & Electrolytes
IMAGS1 “Magnesium sulfate injection” 10 %; 20 ml/amp
用於ACLS (tosade de pointes): 1~2 g/10 ml D5W靜脈推注
用於矯正低血鎂:
[泡法]
3amp in N/S 100ml run 15ml/hr
[備註]
(1) 快速注射可能造成低血壓
(2) 慎用於腎衰竭病患
(3) 鎂含量16.23meq/amp
適應症：產驚、產驚前、孕婦尿毒、產科全身麻醉輔助。
Usual dose:
Eclampsia; treatment and prophylaxis: IV, IM
Adult: initial, 4-5 g in 250 ml D5W or NS and simultaneous doses up to 10 g of undiluted 50% magnesium sulfate solution IM (5 g in each buttock); maintenance, 1-2 g/h IV until paroxysms cease or 4-5 g IM into alternate buttocks q4h as needed; max. daily dose is 30-40 g.
Dose adjustment:
Renal insufficiency, severe: max. dose of magnesium sulfate is 20g/48 h; frequent serum magnesium monitoring recommended.
Contraindication:
Heart block, parenteral administration, myocardial damage, parenteral administration.
Precaution:
Eclampsia, intravenous administration; reserve for life threatening convulsions that need immediate control. Premature neonates; product contains aluminum therefore increasing the risk of aluminum toxicity
Adverse effect:
Serious: abnormal ECG, heart block, hypotension, vasodilatation, blood coagulation disorder with prolonged bleeding time, hyporeflexia, central nervous system depression, respiratory tract paralysis.