Gastrointestinal Agents : Others
OASAC2“Asacol tablet”800 mg/tab
TASAC2 “Asacol suppository”500 mg/pill
TCOLA1 “Colasa enema” 2g/100ml/bot
適應症：
OASAC2：治療潰瘍性結腸炎及其持續治療以防止復發。
TASAC2, TCOLA1：潰瘍性結腸炎、輕度到中度之直腸炎及直腸乙狀結腸炎。
Usual dose:
Adult: Orally, initial, 3-4 gm/day in evenly divided doses not exceeding 8 h intervals; maintenance, 2 gm/day in divided doses not exceeding 8 h intervals. Rectally, enema 4g hs.
Pediatric (≧6 yrs): initial, 40-60 mg/kg/day divided in 3-6 doses; maintenance 30 mg/kg/day divided in 4 doses up to a max of 2 gm/day.
Precaution:
Sulfasalazine intolerance or hypersensitivity; possibility of acute
intolerance syndrome.
Adverse effect:
Common: headache, anorexia, nausea, vomiting, oligospermia,reversible, rash, colitis exacerbation, dizziness, fever, rash ,acne, rectal pain.
Serious: hepatotoxicity; leukopenia, neutropenia, macrocytosis,macrocytic anemia, nephrotoxicity, pulmonary infiltrates, systemic lupus erythematosus.
健保使用規範：限潰瘍性結腸炎、庫隆氏症病例使用。(94/5/1)