Hormones and Agents Affecting Hormonal Mechanism: Antidiabetic Agents: Oral Hypoglycemic Agents
OAMAR2 “Amaryl M FC tablet”
OGLIM2 “Glimet FC tablet”
Each tablet contains metformin HCl 500 mg, glimepiride 2 mg.
適應症：第II型糖尿病。
Usual dose:
Diabetes mellitus type II: initial, 0.5-1 tab/day; maintenance, 0.5-2 tab daily, may divided in 2 doses, max. 4 tab/day.
Contraindication: See metformin HCl/ glimepiride.
Adverse effect:
Common: vomiting (~25.5%), flatulence (12.1% ), hypoglycemia, cobalamin deficiency (~9.9%), diarrhea, malabsorption syndrome (~9.9% ), headache (8.2% ), dizziness (5% ), indigestion (7.1% ), nausea,
Serious: lactic acidosis (rare), cutaneous hypersensitivity (less than 1% ), hepatitis, lichenoid drug eruption, stevens-johnson syndrome.
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