Hormones and Agents Affecting Hormonal Mechanism: Thyroid Disorders
OMETH7 “Methimazole tablet” 5 mg/tab
適應症:甲狀腺機能亢進。
Usual dose:
Hyperthyroidism: PO
Adult: initial, 15 mg (mild); 30 to 40 mg (moderately severe); 60 mg (severe) daily in 3 divided doses 8 h apart; maintenance, 5-15 mg/day.
Pediatric: initial, 0.4 mg/kg/day in 3 divided doses 8 h apart; maintenance, 1/2 of the initial dose.
Contraindication: breast feeding.
Precaution:
Bleeding disorders or easy bruising, signs of infection (fever, headache, malaise, skin eruptions, sore throat).
Adverse effect:
Common: rash.
Serious: agranulocytosis, aplastic anemia, hepatotoxicity.