Methimazole【D】

Hormones and Agents Affecting Hormonal Mechanism: Thyroid Disorders
OMETH7 “Methimazole tablet” 5 mg/tab

適應症:甲狀腺機能亢進。

Usual dose:

Hyperthyroidism: PO

Adult: initial, 15 mg (mild); 30 to 40 mg (moderately severe); 60 mg (severe) daily in 3 divided doses 8 h apart; maintenance, 5-15 mg/day.

Pediatric: initial, 0.4 mg/kg/day in 3 divided doses 8 h apart; maintenance, 1/2 of the initial dose.

Contraindication: breast feeding.

Precaution:

Bleeding disorders or easy bruising, signs of infection (fever, headache, malaise, skin eruptions, sore throat).

Adverse effect:

Common: rash.

Serious: agranulocytosis, aplastic anemia, hepatotoxicity.

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