Misoprostol【X】

Gastrointestinal Agents : Others
OCYTO1 “Cytotec tablet” 200 mcg/tab

適應症:胃及十二指腸潰瘍。

Usual dose:

Abortion: in combination with mifepristone: PO

Adult: 400 mcg/2 days after mifepristone dose of 600mg.

Cervical ripening procedure-induction of labor:

Adult: Intravaginal, 25 mcg q3-4h, max. 400 mcg; PO initial, 100 mcg q4h, max. 5 doses; or initial, 50 mcg q4h for 2 doses, then 100 mcg q4h until membrane rupture, max. of 5 doses.

NSAID-induced gastric ulcer prophylaxis: PO

Adult: 200 mcg qid.

Ulcers- duodenal, gastric: PO

Adult: 800 mcg/day in 2 or 4 divided doses for 4 wks.

Precaution: may cause diarrhea.

Adverse effect:

Abdominal pain, constipation, diarrhea, dyspepsia, flatulence, nausea, dizziness, headache, rash, pruritus, edema, tinnitus, LFT elevations, postmenopausal vaginal bleeding.

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