Cardiovascular – Renal Drugs : Antianginal Agents
OSILV1 “Silvinol tablet” 5 mg/tab
OSIGM1 “Sigmart tablet” 5 mg/tab
適應症：狹心症。
Usual dose:
Stable angina: 10-40 mg bid.
Variant angina: 5-10 mg tid.
Precaution:
Recent myocardial infarction, hypotension, or valvular abnormalities with hemodynamic consequences.
Intraventricular or atrioventricular conduction defects.
Cerebral hemorrhage or recent head trauma; severe liver disease.
Combined therapy with other nitrate derivatives.
Cardiopulmonary bypass surgery.
Adverse effect:
Ischemic heart disease, hypotension, angioneurotic edema, vasodilatation, sinus bradycardia, sinus arrest, flushing, skin rashes, pruritus, photosensitivity, weight gain, edema, abdominal pain, anorexia, diarrhea, nausea, vomiting, muscle aches, headache, malaise/lassitude.
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