Neurologic Drugs : Antiepileptics
OTRIL2 “Trileptal FC tablet” 300 mg/tab
適應症：成人局部癲癇發作之單一或輔助治療，大於三歲孩童癲癇局部發作之輔助治療
Usual dose:
Partial seizure, monotherapy:
Adult: 600-2400 mg/day in 2 divided doses.
Partial seizure; adjunct:
Adult: 600-1200 mg/day in 2 divided doses.
Pediatric (4-16 yrs): initially 8-10 mg/kg in 2 divided doses. Dosage increase: up to 10 mg/kg/day at weekly intervals; max. 46 mg/kg daily in divided doses.
Adverse effect:
Common: abdominal pain, nausea, vomiting, abnormal gait, ataxia, dizziness, headache, nystagmus, somnolence, tremor, vertigo, abnormal vision, diplopia, rhinitis, upper respiratory infection, fatigue.
Serious: Stevens-Johnson syndrome, toxic epidermal necrolysis, hyponatremia, anaphylaxis, immune hypersensitivity reaction, multiorgan, angioedema.
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