Cardiovascular – Renal Drugs : Hyperlipidemia
OLIVA1 “Livalo tablet” 2 mg/tab
- OPITA1 “Pitator tablet” 2 mg/tab
適應症：原發性高膽固醇血症及混合型血脂異常。
Usual dose:
initial, 2 mg orally daily; MAX 4 mg daily; dosage range 1 to 4 mg daily; assess lipid levels 4 weeks after dose initiation or titration.
Dose adjustment:
moderate renal impairment (GFR 30 to 59 mL/min/1.73 m(2)): initial, 1 mg orally daily; MAX 2 mg daily.
severe renal impairment (GFR 15 to 29 mL/min/1.73 m(2) not receiving dialysis): initial, 1 mg orally daily; max. 2 mg daily.
ESRD receiving hemodialysis: initial, 1 mg orally daily; MAX 2 mg daily
concomitant erythromycin: pitavastatin dose should not exceed 1 mg daily.
concomitant rifampin: pitavastatin dose should not exceed 2 mg daily.
Adverse effect:
Common: constipation, diarrhea, backache, myalgia, pain in limb.
Serious: disorder of muscle, rhabdomyolysis.