Hormones and Agents Affecting Hormonal Mechanism: Antidiabetic Agents: Insulin
IHUMU2 “Humulin R injection” 100 IU/ml; 10 ml/vial
IACTR1 “Insulin Actrapid HM injection” 100 IU/ml;10 ml/vial
適應症：糖尿病。
Usual dose:
Diabetes mellitus type I, II:
Adult & Pediatric: SC, individualized.
Diabetic ketoacidosis:
Initial, 0.15 U/kg IV, followed by continuous infusion of 0.1 U/kg/h; if no biochemical response in 2-4 h, double infusion rate; when glucose level falls to 250 mg/dL or less, half infusion rate or add dextrose 5% infusion to maintain blood glucose between 200-250 mg/dL; continue until acidosis is corrected.
DM with hyperosmolar coma; nonketotic:
Initial, 0.1 U/kg IV, followed by continuous infusion of 0.1 U/kg/h until blood glucose falls to 250 mg/dL.
Adverse effect:
Common: cutaneous hypersensitivity, injection site reaction, hypoglycemia, lipodystrophy.
Serious: hypooglycemia.
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