Gastrointestinal Agents : Laxatives
OFLEE1 “Fleet phospho-soda oral saline laxative”
Each 15 ml contain monobasic sodium phosphate 7.2 g, dibasic sodium phosphate 2.7 g; 45 ml/bot
OFULI1“Fulisay Oral Solution”
Each ml contain sodium phosphate monobasic monohydrate 480mg, sodium phosphate dibasic heptahydrate 180mg; 45 ml/bot
適應症：緩解偶發性便秘、手術前、X光或內視鏡檢查前之腸灌洗。
Usual dose: PO, diluted with around 240 ml water or cold clear drink.
Constipation: 30 min before a meal or on an empty stomach.
Adult & children (≧12 years): Dilute 15 mL in 240 mL liqd & drink at least 240 mL. Max: 45 mL/24 hr.
Children: 10-11 years: Dilute 15 mL in 240 mL liqd & drink at least 240 mL. Max: 15 mL/24 hr.
Children:5-9 years: Dilute 7.5 mL in 240 mL liqd & drink at least 240 mL. Max: 7.5 mL/24 hr.
Bowel cleansing regimen
Prior to surgery or x-ray & endoscopic exam 45 mL in the evening before exam, 45 mL in the morning of exam.
Dilute recommended dose with 1/2 glass of water, drink then followed with 1 full glass of water.
Contraindication:
Congenital megacolon, intestinal obstruction or congestive heart failure; children < 5 years.
Precaution:
Renal disease or low salt diet.
Pregnancy, lactation. When nausea, vomiting, abdominal pain, sudden change in bowel movement are present.
Discontinue if rectal bleeding.
Renal impairment, electrolyte imbalance, over-fatigue, co-administration of diuretics or other drugs affecting electrolyte imbalance.
Adverse effect:
Common: hyperphosphatemia, hypokalemia, abdominal bloating, abdominal pain, nausea, vomiting.
Serious: prolonged QT interval, tonic-clonic seizure, acute phosphate nephropathy, renal failure.