Antineoplastic Agents: Hormones and Antagonists
ONOLV1 “Nolvadex tablet” 10 mg/tab
適應症:轉移性乳癌之治療、乳癌手術後之輔助療法。
Usual dose:
Adult: 20-40 mg/day, qd or divided twice a day.
Contraindication: concomitant coumarin-type anticoagulant therapy, deep vein thrombosis p’ts, pulmonary embolus.
Adverse effect:
Common: hot sweats, amenorrhea, disorder of menstruation, irregular periods, vaginal discharge.
Serious: cerebrovascular accident, cataract, cataract surgery, malignant neoplasm of endometrium of corpus uteri, pulmonary embolism.