Teicoplanin【N/A】

Anti-infective Agents : Miscellaneous antibacterials

ITARG1 “Targocid injection” 200 mg/vial

ITARG2 “Targocid injection” 400 mg/vial

ITECO1 “Tecopin injection” 400 mg/vial

適應症：葡萄球菌感染所致之心內膜炎、骨髓炎、肺炎、敗血病、軟組織感染、腸炎、梭狀桿菌感染所致之假膜性結腸炎。

Usual dose:

Adult: initially, 400 or 6 mg/kg, followed by 200 mg or 3 mg/kg/day; severe infection, 400 mg q12h × 3 dose, followed by 400 mg/day, max. 12mg/kg/day.

Pediatric (2-12 yrs): initially, 6 mg/kg q12h × 3 dose, followed by 3-6 mg/kg/day, max. 10-20 mg/kg/day.

Dose adjustment:

Renal failure:

CrCl (ml/min)	> 80	30-80	< 10
constant interval (q24h)	400 mg	200 mg	133 mg
constant dose (400 mg)	q24h	q48h	q72h

Adverse effect:

Common: rash, diarrhea, injection site pain.

Serious: neutropenia, eosinophilia, spontaneous platelet aggregation, thrombocytopenia and leucopenia with neutropenia.

健保使用規範：1.對其他抗生素有抗藥性之革蘭氏陽性菌感染；2.對其他抗生素有嚴重過敏反應之革蘭氏陽性菌感染。