Neurologic Drugs : Huntington’s disease
OXENA1 “Xenazine tablet” 25 mg/tab
適應症:治療亨汀頓舞蹈症之舞蹈症狀。
Usual dose:
Initial, 12.5 mg qd; increase dose at minimum 1 wk intervals in 12.5 mg increments to 25 mg/day (12.5 mg bid), max. 50 mg/day.
Adverse effect:
Common: dysphagia, nausea, akathisia, insomnia, parkinsonism, somnolence, upper respiratory infection, fatigue
Serious: prolonged QT interval, depression, neuroleptic malignant syndrome