Theophylline monohydrate【C】

Respiratory Tract Drugs: Bronchodilators
OTELI1 “Telin SR tablet” 200 mg/tab
OXANT2 “Xanthium SR capsule” 400 mg/cap

適應症:氣喘及支氣管痙攣。

Usual dose:

Adult (≧17 yrs): 600-1000 mg q24h or 300-500 mg q12h.

Pediatric

(12-16 yrs): 600-800 mg q24h or 300-400 mg q12h.

(9-12 yrs): 400-600 mg q24h or 200-300 mg q12h.

(6-9 yrs): 400 mg q24h or 200 mg q12h.

Dose adjustment:

Geriatric: loading dose 5 mg/kg; maintenance 2 mg/kg q8h.

Adverse effect:

Common: nausea, vomiting, headache, insomnia, tremor, restlessness.

Serious: atrial fibrillation, tachyarrhythmia, Stevens-Johnson syndrome, intracranial hemorrhage, seizure.

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