Agents Used to Treat Urological Disorders
OURID1 “Uridin FC tablet” 2 mg/tab
ODETR2 “Detrusitol SR capsule” 4 mg/cap
適應症：治療伴有尿急、頻尿或急迫性尿失禁症狀的膀胱過動症。
Usual dose:
Adult: 4 mg qd, dosage may be reduced to 2 mg qd according to individual response and tolerance.
Dose adjustment:
Renal impairment (CrCl 10-30 ml/min), liver disease, concomitantly using CYP3A4 inhibitors: 2 mg qd.
Contraindication:
Gastric retention, uncontrolled narrow-angle glaucoma, urinary retention.
Precaution: history of QT prolongation, myasthenia gravis., bladder outflow obstruction.
Adverse effect:
Common: constipation, xerostomia, headache.
Serious: anaphylactoid reaction, dementia, memory impairment, angioedema.
健保使用規範：(90/7/1、93/10/1、96/4/1)
1.限符合下列診斷標準條件之一者：(1)頻尿：每天（24小時）排尿次數超過八次，並有詳實病歷紀錄；(2)急尿：病患自述經常有一種很突然、很強烈想解尿的感覺；(3)急迫性尿失禁：對於尿急的感覺無法控制，並於24小時內至少也有一次漏尿之情形。
2.不宜使用本類藥品者：(1)小兒夜尿；(2)單純性應力性尿失禁；(3)膀胱逼尿肌無反射(detrusor areflexia)或膀胱不收縮所引起之排尿困難或尿失禁之症狀。