Antineoplastic Agents: Cytotoxic Agents: Antimetabolites
OTS1 “TS-1 capsule”
Each capsule contains tegafur 20mg, gimeracil 5.8 mg, oteracil potassium 19.6 mg
適應症:胃癌術後輔助性化療,用於罹患TNM STAGE II (排除TI),IIIA或IIIB胃癌且接受過胃癌根除性手術的成年患者。治療無法切除的晚期胃癌。適用於治療局部晚期或轉移性胰臟癌病人。
Usual dose:
Adult: BSA < 1.25 m2: 80 mg/day; BSA 1.25-1.5 m2: 100 mg/day; BSA ≥ 1.5 m2: 120 mg/day, max. 75 mg/dose, min. 40 mg/dose.
Adverse effect:
Common: N/V, diarrhea, constipation, anemia, anorexia.
Serious: neutropenia, severe hepatopathy, dehydration, severe enteritis.
健保使用規範:治療局部晚期無法手術切除或轉移性胰臟癌病人。(103/6/1)