Cardiovascular – Renal Drugs : Antihypertensive : Angiotensin II Antagonist (ARB)
OCODA1 “Co-Daianxo capsule”
Each capsulet contains valsartan 80 mg, hydrochlorothiazide 12.5 mg
OCODI1 “Co-Diovan FC tablet”
Each tablet contains valsartan 80 mg, hydrochlorothiazide 12.5 mg
適應症：單一療法無法控制的高血壓，做為第二線用藥。
Usual dose:
Hypertension, not for initial therapy:
Adult: initial, valsartan 80 mg/hydrochlorothiazide 12.5 mg qd; may titrate dose at 3-4 week intervals up to valsartan 320 mg/hydrochlorothiazide 25 mg qd, based on clinical response
Dose adjustment:
Renal impairment: not recommended in p’ts with CrCl < 30 ml/min
Contraindication:
Anuria, and reaction more likely with history of allergy or bronchial asthma.
Adverse effect:
Common: hypotension, diarrhea, dizziness, headache, serum blood urea nitrogen raised, serum creatinine raised, cough, fatigue
Serious: hepatitis, renal failure, angioedema (face, lips, throat).