Antineoplastic Agents: Cytotoxic Agents: Mitotic Inhibitors
IVINC9 “Vincristine injection” 1 mg/ml; 1 ml/vial
適應症：急性白血病。
Usual dose:
Adult: 0.03-1.4 mg/m2/wk IV.
Pediatric
(>10 kg): 1.5-2mg/m2 IV once weekly, varies per protocol.
(≦10kg): 0.05 mg/kg IV once weekly, varies per protocol.
Dose adjustment:
Hepatic: 50% reduction in dose of vincreistin if the direct serum bilirubin value is above 3 mg/100 ml.
Adverse effect:
Common: alopecia, constipation, diplopia, nausea/vomiting.
Serious: myelosuppression.
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