Psychopharmacologic Drugs : Antipsychotics
OGEOD1 “Geodon capsule” 40 mg/cap
OGEOD6 “Geodon capsule” 60 mg/cap
適應症：精神分裂症、雙極性疾患之躁症發作及在雙極性疾患躁症發作（Bipolar I disorder）之維持治療中，作為鋰鹽或valproate的輔助療法。
Usual dose:
Bipolar I disorder, acute manic or mixed episodes: day 1, 40 mg bid with food; day 2, 60 or 80 mg bid; then adjust to 40 -80 mg bid.
Schizophrenia: initial, 20 mg bid with food; may increase dosage q2d up to 80 mg bid; maintenance, 20-80 mg bid, max. 80 mg bid.
Contraindication:
QT-interval prolongation, acute MI, uncompensated heart failure, cardiac arrhythmias requiring treatment with Class I & III antiarrhythmic drugs.
Adverse effect:
Common: orthostatic hypotension, rash, constipation, diarrhea, indigestion, nausea., akathisia, dizziness, extrapyramidal disease, somnolence, cough, rhinitis.
Serious: prolonged QT interval, syncope, torsades de pointes, diabetes mellitus, hyperglycemia, neuroleptic malignant syndrome, seizure, tardive dyskinesia, priapism, death.
健保使用規範：
1.需合乎衛生主管機關許可之適應症範圍，並需符合下列條件 (1)開始使用「第二代抗精神病藥品」時需於病歷記載：醫療理由或診斷，以及臨床整體評估表(CGI)之分數；(2)經規則使用六至八週後，需整體評估其療效，並於病歷記載：臨床整體評估表之分數；(3)日劑量超過時120 mg/day，須於病歷記載理由。
2.本類藥品不得使用於雙極性疾患之鬱症發作。(95/10/1)