Cardiovascular – Renal Drugs : Antihypertensive : Sympathetic Depressants
OATIN1 “Atinol FC tablet” 50 mg/tab
OATEO1 “Ateol FC tablet” 100 mg/tab
適應症：高血壓、狹心症。
Usual dose:
Angina:
Adult: initial, 50 mg qd. max. 200 mg qd titrate to maintenance after 1 wk, 50-100 mg qd.
Cardiac dysrhythmia:
Adult: 50-100 mg qd.
Pediatric: initial, 0.3-1.4 mg/kg qd, may increase by 0.5 mg/kg/day increments q3-4d; max. 2 mg/kg qd.
Hypertension:
Adult: 50-100 mg qd.
Pediatric: initial, 0.5-1 mg/kg/day qd-bid, max. 2 mg/kg/day up to 100 mg/day qd-bid.
Migraine headache, prophylaxis:
Adult: 50-100 mg qd.
Dose adjustment:
Renal impairment: CrCl≧35 ml/min – normal dosing, CrCl 15-35 ml/min – max.50 mg qd, CrCl < 15 ml/min –max. 25 mg qd.
Contraindication:
Cardiogenic shock, hypersensitivity to atenolol, overt cardiac failure, second and third degree AV block, severe sinus bradycardia.
Adverse effect:
Common: cold extremities, hypotension, dizziness, depression, insomnia, tiredness, diarrhea, nausea, bradycardia.
Serious: lupus syndrome.