Hormones and Agents Affecting Hormonal Mechanism: Calcium Regulating Agents
IMIAC1 “Miacalcic injection” 50 IU/ml; 1 ml/amp
適應症:高血鈣危象、骨骼的帕哲特氏病、斷經後引起之骨骼疏鬆。
Usual dose:
Hypercalcemia: initial, 4 IU/kg SC or IM q12h; may increase after 1-2 days to 8 IU/kg q12h; may increase after another 2 days to a max. of 8 IU/kg q6h.
Paget’s disease: initial, 100 IU SC or IM daily.
Postmenopausal osteoporosis: 100 IU SC or IM qod; 200 IU (1 spray) intranasally qd, alternating nostrils daily.
Precaution:
Administration of calcitonin possibly could lead to hypocalcemic tetany.
Adverse effect:
Common: flushing, face or hands, injection, injection site inflammation, nausea, vomiting, injection, backache, nasal, rhinitis, nasal.
Serious: myocardial infarction, thrombophlebitis, anemia, anaphylaxis, cerebrovascular accident, bronchospasm, few cases.
健保使用規範:用於惡性疾病之高血鈣症或變形性骨炎 ( Paget’s disease)(85/10/1、93/8/1、100/1/1、103/2/1)。