Anti-infective Agents : Cephalosporins : Third Generation Cephalosporins
ICEFT1 “Ceftriaxone powder for injection” 1 gm/vial
IROCE1 “Rocephin injection” 500 mg/vial
ISINT1 “Sintrix injection” 1 gm/vial
適應症:葡萄球菌、鏈球菌、肺炎雙球菌、腦膜炎球菌及具他具有感受性細菌引起之感染症。
Usual dose: IV/IM
Adult: 1-2 g q12h-24h, max. 4 g/day.
Pediatric: 50-75 mg/kg/day qd or divided bid.
Contraindication: hyperbilirubinemic neonates.
Precaution:
IV, max. conc. for infusion is 40 mg/ml, give over 30 min;do not concurrently administer calcium-containing IV solutions in same IV line.
Dose adjustment:
Combined renal and hepatic impairment: doses should < 2 g/day.
Adverse effect:
Common: injecjection site pain, rash, diarrhea, increased liver enzymes.
Serious: hemolysis, disease of gallbladder.
健保使用規範:用於疑似或證實為淋病尿道炎、子宮頸炎、軟性下疳時,可第一線單一劑量使用。(95/6/1)