Cardiovascular – Renal Drugs : Hyperlipidemia
OLIPA2 “Lipanthyl Supra FC tablet” 160 mg/tab
OSYNP2 “Synpid FC tablet” 160 mg/tab
適應症：高膽固醇血症、高三酸甘油脂血症、混合型高血脂症(TYPE IIa, IIb, III, IV, V)。
Usual dose:
Hypercholesterolemia, (Frederickson Type IIa, IIb):
Adult: initial dose, 160 mg/day with meals.
Hypertriglyceridemia, (Frederickson Types IV and V):
Adult: initial dose, 54-160 mg/day with meals.
Dose adjustment:
Renal impairment, mild to moderate, Tricor(R): 54 mg orally daily initially.
Contraindication:
Active liver disease, including primary biliary cirrhosis, and
unexplained persistent liver function abnormalities.
Gallbladder disease, nursing mothers.
Severe renal impairment, including patients with end-stage renal
disease or those receiving dialysis.
Precaution:
Severe HDL decreases, gastrointestinal, Stevens-Johnson
syndrome, toxic epidermal necrolysis, dose-related increases in serum transaminases, rhabdomyolysis.
Adverse effect:
Common:
Rash,Diarrhea, flatulence, nausea and vomiting, myalgia, rhinitis
Serious:
Pancreatitis (rare), hepatotoxicity (rare), rhabdomyolysis (rare).
健保使用規範：同atorvastatin。