Hematological Agents : Deficiency Anemia
OFOLA1 “Folacin tablet” 5 mg/tab
適應症：惡性貧血、妊孕期之貧血、小兒巨大紅血球貧血及骨髓增生或衰退引起之貧血。
Usual dose:
Adult: initial, up to 1 mg/day; maintenance, 0.4 mg/day; pregnant women: initial, up to 1 mg/day; maintenance, 0.8 mg/day.
Pediatric: up to 1 mg/day; maintenance, (infants), 0.1 mg/day; (< 4 yrs), up to 0.3 mg/day; (≧4 yrs), 0.4 mg/day.
Recommended dietary allowance:
Adult
(male): 400 mcg/day.
(female): 400 mcg/day; pregnancy 600 mcg/day; lactation, 500 mcg/day.
Pediatric (≦1 yr), 65-80 mcg/day; (1-3 yrs), 150 mcg/day; (4- 8 yrs), 200 mcg/day; (9-13 yrs), 300 mcg/day; (14-18 yrs), 400 mcg/day.
Dose adjustment:
Alcoholism, hemolytic anemia, anticonvulsant therapy, chronic infection: maintenance dose may need to be increased.
Adverse effect:
Common: anorexia, nausea, bitter/bad taste (large doses), irritability, confusion, altered sleep pattern (large doses)
Serious: allergic sensitization.