Pentoxifylline【C】

Cardiovascular – Renal Drugs
OFYLI1 “Fylin retard FC tablet” 400 mg/tab

適應症:末稍血管循環障礙。

Usual dose:

Intermittent claudication: PO, 400 mg tid with meals.

Stasis ulcer: PO, 800 mg tid with meals.

Vascular disorder of inner ear: 1600 mg/day in 2-4 divided doses.

Dose adjustment:

Renal impairment: CrCl 10-50 ml/min, 400 mg q12-24h, CrCl < 10 ml/min, 400 mg q24h.

Contraindication:

Recent cerebral hemorrhage, recent retinal hemorrhage.

Adverse effect:

Common: indigestion, nausea, vomiting dizziness, headache.

Serious: angina, edema, hypotension, arrhythmias, confusion, depression, seizure, aplastic anemia, leukopenia, thrombocytopenia, hepatitis, jaundice, elevated LFTs.

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