Gastrointestinal Agents : Others
OSALA3 “Salazine EC tablet” 500 mg/tab
適應症：潰瘍性結腸炎、類風濕性關節炎。
Usual dose:
Rheumatoid arthritis:
Adult: initial, 0.5-1 gm/day qd or bid; maintenance, 1 gm bid, max. 3 gm/day.
Pediatric (> 6 yrs): 30-50 mg/kg/day bid, max. 2 gm/day.
Ulcerative colitis:
Adult: initial, 3-4 gm/day in evenly divided doses not exceeding 8 h intervals; maintenance, 2 gm/day in divided doses not exceeding 8 h intervals.
Pediatric (> 6 yrs): initial, 40-60 mg/kg/day divided in 3-6 doses; maintenance 30 mg/kg/day qid, max. 2 gm/day.
Adverse effect:
Common: headache, anorexia, nausea, vomiting, oligospermia, reversible, rash.
Serious: hepatotoxicity, leukopenia, neutropenia, macrocytosis,macrocytic anemia, nephrotoxicity, pulmonary infiltrates, systemic lupus erythematosus.
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