Ulceration is limited to the overlying mucosa, whereas the surrounding mucosa appears histologically normal.
Possible mechanism
♥This proclivity is attributed to the blood supply to this area coming directly from the arterial chain running along the lesser gastric curve because the usual submucosal, arterial anastomotic gastric plexus is absent in this area.
♥ Extra-GI location: bronchus and gallbladder.
♥ Other GI symptoms, especially abdominal pain, are uncommon and their presence suggests alternative diagnoses such as peptic ulcer disease or complications from the bleeding such as mesenteric ischemia from hemorrhagic shock.
♥ Multiple or disseminated Dieulafoy’s lesions have not been reported. One patient, however, had two GI Dieulafoy’s lesions.